Associations between endocrine disrupting chemicals and equine metabolic syndrome phenotypes
نویسندگان
چکیده
منابع مشابه
Endocrine disrupting chemicals
The idea that xenobiotic chemicals could inappropriately modlate the endocrine system thereby causing detrimental effects n wildlife and humans was first proposed 20 years ago at the atershed Wingspread Conference [1,2]. These endocrine disruptng chemicals (EDCs) have long been controversial, with a great eal of discussion raging in the scientific literature. Much of this ontroversy has centere...
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Prospective clinical studies have suggested that the rate of congenital cryptorchidism has increased since the 1950s. It has been hypothesized that this may be related to environmental factors. Testicular descent occurs in two phases controlled by Leydig cell-derived hormones insulin-like peptide 3 (INSL3) and testosterone. Disorders in fetal androgen production/action or suppression of Insl3 a...
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Endocrine disrupting activities in industrial chemicals have been a serious problem, because they are distributed broadly, they are active at very low concentrations, and some of them are difficult to detoxify. Moreover, only a small number of active chemicals are known, while most chemicals have not been examined yet. To reduce the number of examinations required for unknown chemicals, some co...
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Endocrine-disrupting chemicals are substances present in the environment that can interfere with normal hormonal balance and thus exert potentially adverse health effects on the human organism. Male reproductive system development and function may be susceptible to the effects of such environmental toxicants. Bisphenol A, phthalates and alkylphenols are important components of multiple products...
متن کاملEndocrine disrupting chemicals and disease susceptibility.
Environmental chemicals have significant impacts on biological systems. Chemical exposures during early stages of development can disrupt normal patterns of development and thus dramatically alter disease susceptibility later in life. Endocrine disrupting chemicals (EDCs) interfere with the body's endocrine system and produce adverse developmental, reproductive, neurological, cardiovascular, me...
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ژورنال
عنوان ژورنال: Chemosphere
سال: 2019
ISSN: 0045-6535
DOI: 10.1016/j.chemosphere.2018.11.136